Zyclastin 4 mg Injection

Zyclastin 4mg Injection – Zoledronic Acid for Injection IP by Zydus

Zyclastin 4mg Injection from Zydus Oncosciences contains Zoledronic Acid for Injection IP 4 mg as a lyophilised powder for intravenous infusion. As a bisphosphonate it attaches to bone mineral and inhibits osteoclasts – the cells responsible for breaking bone down – which raises bone density and pulls down the excess calcium released into the blood when resorption runs unchecked. It is used for osteoporosis in postmenopausal women and in people on long-term corticosteroids, and to control the high blood calcium that some cancers cause. Single-dose vial. Prescription medicine, given only by a healthcare professional.

Key Features

• Zoledronic Acid for Injection IP 4 mg lyophilised powder
• Single-dose vial for IV infusion only
• Bisphosphonate that inhibits osteoclast-driven bone breakdown
• Used in osteoporosis and cancer-related hypercalcaemia
• From Zydus Oncosciences

Composition

• Zoledronic Acid for Injection IP – 4 mg per single-dose vial

Refer to the pack label and package insert for the complete list of excipients.

Uses & Benefits

• Treats and prevents osteoporosis in postmenopausal women
• Used for osteoporosis in men and in people on corticosteroid therapy
• Brings down high blood calcium caused by some cancers
• Reduces skeletal complications in bone metastases and multiple myeloma
• Increases bone mineral density and helps lower fracture risk
• Long dosing intervals compared with daily oral bisphosphonates

Directions for Use

• Administered by a healthcare professional only – never self-inject
• Reconstitute and dilute strictly as directed in the package insert
• Infuse intravenously over at least 15 minutes
• Ensure good hydration before the infusion to protect the kidneys
• Do not mix with calcium-containing infusion solutions

Precautions

• Do not use if the reconstituted solution is discoloured or contains visible particles
• Kidney injury is the main risk – kidney function is checked before each dose, and the risk rises with dehydration or other nephrotoxic drugs
• Osteonecrosis of the jaw can occur – complete any dental work before starting, keep good oral hygiene, and report jaw pain or swelling
• Can cause low blood calcium – calcium and vitamin D are usually prescribed alongside
• A flu-like reaction (fever, headache, muscle and joint aches) is common after the first dose and usually settles in a few days
• Not recommended in pregnancy or breastfeeding. Report unusual thigh or groin pain, which can signal an atypical femoral fracture

Storage

• Store below 30°C, protected from light
• Use the reconstituted solution promptly; do not store part-used vials
• Keep out of reach of children

Disclaimer

Schedule H prescription drug – to be sold by retail only on the prescription of a Registered Medical Practitioner, and administered under medical supervision. This information is for general awareness only and is not a substitute for professional medical advice, diagnosis or treatment.