Xolnic 4 mg Injection

Xolnic 4mg Injection – Zoledronic Acid IP 4 mg by Khandelwal

Xolnic 4mg Injection from Khandelwal Laboratories contains Zoledronic Acid Monohydrate IP equivalent to 4 mg of anhydrous zoledronic acid, supplied as a lyophilised powder for single intravenous use. Zoledronic acid is the most potent of the bisphosphonates: it binds tightly to bone mineral and shuts down osteoclasts, the cells that dissolve bone. Suppressing that breakdown strengthens the skeleton and brings down the calcium that unchecked bone resorption releases into the bloodstream. The pack is marked “as directed by the Oncologist”, reflecting its main use in cancer-related bone disease. Prescription medicine – administered by a healthcare professional.

Key Features

• Zoledronic Acid IP 4 mg per vial, lyophilised powder
• For single intravenous use only – one vial, one dose
• Most potent bisphosphonate class for bone protection
• Widely used in oncology for bone metastases and hypercalcaemia
• Manufactured in India by Khandelwal Laboratories Pvt. Ltd., Thane

Composition

• Zoledronic Acid Monohydrate IP equivalent to anhydrous Zoledronic Acid – 4 mg per vial

Refer to the pack label and package insert for the complete list of excipients.

Uses & Benefits

• Lowers high blood calcium (hypercalcaemia) caused by cancer
• Reduces skeletal complications from bone metastases of solid tumours
• Used in multiple myeloma to protect bone
• Treatment of osteoporosis, including postmenopausal and steroid-induced
• Helps relieve bone pain associated with metastatic disease
• Increases bone mineral density and lowers fracture risk

Directions for Use

• Dosage as directed by the oncologist or treating physician
• Administered by a healthcare professional only – never self-inject
• Reconstitute and dilute strictly per the package insert, then infuse over at least 15 minutes
• Drink plenty of water before the infusion – good hydration protects the kidneys
• Do not mix with calcium-containing infusion solutions such as Ringer’s lactate

Precautions

• Do not use if the reconstituted solution is discoloured or contains visible particles
• Kidney injury is the main risk – the danger rises with dehydration or other kidney-affecting drugs, and renal function is checked before each dose
• Osteonecrosis of the jaw can occur – complete any needed dental work before starting, keep good oral hygiene, and report jaw pain, swelling or a loose tooth
• Can cause low blood calcium – calcium and vitamin D are usually prescribed alongside
• A flu-like reaction (fever, headache, muscle and joint aches) is common after the first dose and usually settles within a few days
• Not recommended in pregnancy or breastfeeding. Report unusual thigh or groin pain, which can signal an atypical femoral fracture

Storage

• Store below 30°C, protected from light
• Use the reconstituted solution promptly; single-dose vial – discard any remainder
• Keep out of reach of children

Disclaimer

Prescription medicine – to be sold by retail only on the prescription of a Registered Medical Practitioner, and administered under medical supervision. This information is for general awareness only and is not a substitute for professional medical advice, diagnosis or treatment.