Syndopa Plus Tablet

Syndopa Plus Tablet – Levodopa 100 mg + Carbidopa 25 mg by Sun Pharma

Syndopa Plus from Sun Pharma contains Levodopa IP 100 mg and Carbidopa (anhydrous) IP 25 mg in an uncoated tablet – the cornerstone treatment for Parkinson’s disease. Dopamine itself cannot be given as a medicine because it will not cross from blood into brain. Levodopa can, and the brain converts it to dopamine on arrival. The difficulty is that the same conversion happens throughout the body first, so most of a levodopa dose is wasted in the bloodstream – and the dopamine produced there causes severe nausea. Carbidopa solves both problems at once: it blocks that conversion outside the brain but cannot enter the brain itself, so far more levodopa arrives where it is needed and far less nausea results. Strip of 15 tablets. Schedule H prescription medicine.

Key Features

• Levodopa IP 100 mg + Carbidopa (anhydrous) IP 25 mg per uncoated tablet
• The standard first-line treatment for Parkinson’s disease
• Carbidopa blocks breakdown outside the brain – more levodopa reaches the brain, with far less nausea
• Improves tremor, rigidity and slowness of movement
• Strip of 15 tablets from Sun Pharmaceutical Industries Ltd.

Composition

• Levodopa IP – 100 mg
• Carbidopa (Anhydrous) IP – 25 mg
• Per uncoated tablet

Composition as printed on the pack. Refer to the package insert for the complete list of excipients.

Uses & Benefits

• Reduces the tremor, stiffness and slowness of Parkinson’s disease
• Restores dopamine that the brain can no longer make in sufficient amounts
• Carbidopa lets far more levodopa reach the brain, so a smaller dose works
• Markedly reduces the nausea plain levodopa causes
• Improves the ability to walk, write, dress and manage daily tasks
• The most effective symptomatic treatment available for Parkinson’s disease

Directions for Use

• Take exactly as prescribed – the dose and timing are worked out individually and adjusted over time
• Take it at the same times every day. With this medicine timing matters more than with almost any other; a late dose can mean symptoms return
• Avoid taking it with a high-protein meal – dietary protein competes with levodopa for absorption and can blunt the dose
• If nausea troubles you, a light non-protein snack with the dose can help. Ask your doctor first
• Never stop suddenly. Abrupt withdrawal can cause a dangerous reaction with fever and muscle rigidity

Precautions

• Do not stop this medicine abruptly – sudden withdrawal can trigger a severe reaction with high fever and muscle stiffness needing emergency care
• Dizziness on standing is common, particularly early on. Rise slowly from sitting or lying
• Sudden sleep attacks can occur without warning drowsiness – do not drive or operate machinery until you know how this affects you
• Involuntary writhing movements (dyskinesia) may develop after long use, and the effect of each dose may start wearing off early. Report both – the regimen can be adjusted
• Impulse control problems (gambling, compulsive shopping, eating or sexual urges) have been reported. Tell your doctor or family if behaviour changes
• Urine, sweat or saliva may darken. This is harmless
• Tell your doctor about glaucoma, heart disease, ulcers, kidney or liver disease, or a history of melanoma; do not take with MAO inhibitors

Storage

• Store at room temperature, protected from light and moisture, as printed on the pack
• Keep tablets in the original blister until use
• Keep out of reach of children

Disclaimer

Schedule H prescription drug – to be sold by retail on the prescription of a Registered Medical Practitioner only. This information is for general awareness and is not a substitute for professional medical advice, diagnosis or treatment. Parkinson’s treatment must be planned and adjusted only by your treating neurologist.