Syndopa 275 Tablet – Levodopa 250 mg + Carbidopa 25 mg by Sun Pharma
Syndopa 275 from Sun Pharma contains Levodopa IP 250 mg and Carbidopa IP 25 mg in an uncoated tablet – the numbers in the name simply add up to 275. This is the higher-strength levodopa tablet, two and a half times the 100 mg dose, prescribed as Parkinson’s progresses and the earlier strength no longer controls symptoms through the day. Note that the carbidopa stays at 25 mg: carbidopa is not there to treat anything, only to stop levodopa being broken down before it reaches the brain, and around 25 mg per dose is enough to saturate that job. Strip of 10 tablets. Schedule H prescription medicine.
Key Features
- Levodopa IP 250 mg + Carbidopa IP 25 mg per uncoated tablet
- Higher levodopa strength for more advanced disease
- Carbidopa held at 25 mg – the amount needed to block peripheral breakdown
- Improves tremor, rigidity, slowness and walking
- Strip of 10 tablets from Sun Pharmaceutical Industries Ltd.
Composition
- Levodopa IP – 250 mg
- Carbidopa IP – 25 mg
- Per uncoated tablet
Composition as printed on the pack. Refer to the package insert for the complete list of excipients.
Uses & Benefits
- Reduces the tremor, stiffness and slowness of Parkinson’s disease
- Restores dopamine the brain can no longer make in sufficient amounts
- Carbidopa lets far more levodopa reach the brain, so a smaller dose works
- Markedly reduces the nausea plain levodopa causes
- Improves the ability to walk, write, dress and manage daily tasks
- The most effective symptomatic treatment available for Parkinson’s disease
Directions for Use
- Take exactly as prescribed – the dose and timing are worked out individually and adjusted over time
- Take it at the same times every day. With this medicine timing matters more than with almost any other; a late dose can mean symptoms return
- Avoid taking it with a high-protein meal – dietary protein competes with levodopa for absorption and can blunt the dose
- If nausea troubles you, a light non-protein snack with the dose can help. Ask your doctor first
- Never stop suddenly. Abrupt withdrawal can cause a dangerous reaction with fever and muscle rigidity
Precautions
- Do not stop this medicine abruptly – sudden withdrawal can trigger a severe reaction with high fever and muscle stiffness needing emergency care
- Dizziness on standing is common, particularly early on. Rise slowly from sitting or lying
- Sudden sleep attacks can occur without warning drowsiness – do not drive or operate machinery until you know how this affects you
- Involuntary writhing movements (dyskinesia) may develop after long use, and each dose may start wearing off early. Report both – the regimen can be adjusted
- Impulse control problems (gambling, compulsive shopping, eating or sexual urges) have been reported. Tell your doctor or family if behaviour changes
- Urine, sweat or saliva may darken. This is harmless
- Tell your doctor about glaucoma, heart disease, ulcers, kidney or liver disease, or a history of melanoma; do not take with MAO inhibitors
Storage
- Store at room temperature, protected from light and moisture
- Keep tablets in the original blister until use
- Keep out of reach of children
Disclaimer
Schedule H prescription drug – to be sold by retail on the prescription of a Registered Medical Practitioner only. This information is for general awareness and is not a substitute for professional medical advice, diagnosis or treatment. Parkinson’s treatment must be planned and adjusted only by your treating neurologist.













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