Rabekind-DSR Capsule

Rabekind-DSR Capsule – Rabeprazole Sodium 20 mg + Domperidone SR 30 mg by Mankind

Rabekind-DSR from Mankind Pharma is a hard gelatin capsule of Rabeprazole Sodium IP 20 mg as gastro-resistant pellets and Domperidone IP 30 mg as sustained-release pellets. The pairing targets two different problems that often occur together. Acid reflux is not always simply a matter of too much acid – in many people the stomach also empties too slowly, so food and acid sit there longer and press back against the valve at the top of the stomach. A proton pump inhibitor alone reduces the acid but does nothing about the delay; domperidone is a prokinetic that makes the stomach contract more effectively and empty faster, which addresses the mechanical half of the problem. That is why this combination is prescribed for reflux accompanied by bloating, fullness, nausea and belching rather than for plain heartburn. Domperidone belongs in short courses, not open-ended use. Strip of 10 capsules.

Key Features

• Rabeprazole Sodium IP 20 mg (gastro-resistant pellets) + Domperidone IP 30 mg (sustained release pellets)
• For reflux that comes with bloating, fullness, nausea or belching
• Swallow the capsule whole – do not open or crush it
• Colours: Ferric Oxide Red USP-NF, Brilliant Blue FCF and Titanium Dioxide IP
• Strip of 10 capsules, marketed by Mankind Pharma Ltd.

Composition

• Rabeprazole Sodium IP – 20 mg (as gastro-resistant pellets)
• Domperidone IP – 30 mg (as sustained release pellets)
• Colours: Ferric Oxide Red USP-NF, Brilliant Blue FCF & Titanium Dioxide IP. Approved colours in the hard gelatin capsule shell

Uses & Benefits

• Treats acid reflux that comes with bloating, fullness, nausea or belching
• The rabeprazole reduces acid production; the domperidone speeds up stomach emptying
• Useful in non-ulcer dyspepsia and in reflux linked to slow gastric emptying
• Relieves the sensation of food sitting in the stomach after meals
• Reduces nausea and vomiting alongside the acid symptoms
• One capsule daily before breakfast, for a short prescribed course

Directions for Use

• Swallow the capsule whole with water. Do not open, chew or crush it – it contains two different pellet types with two different release profiles
• Take it 30 to 60 minutes before a meal, usually before breakfast, or exactly as your doctor directs
• Take it at the same time each day, for the period your doctor sets
• If you miss a dose, take it when you remember unless the next is nearly due. Never double up
• This combination is meant for short courses. Ask your doctor before continuing it beyond the prescribed period

Precautions

• This combination contains domperidone. Domperidone can affect heart rhythm by prolonging the QT interval, so it should be used at the lowest effective dose for the shortest possible time – usually no more than a week without review
• Tell your doctor about any heart condition, heart rhythm problem, or low potassium or magnesium, and about medicines that also prolong QT such as certain antibiotics, antifungals and antidepressants
• Do not use it if you have a gastrointestinal bleed, blockage or perforation – speeding the gut up in those situations is dangerous
• Take the capsule 30 to 60 minutes before food and swallow it whole; never open or crush it
• Tell your doctor about liver disease, kidney disease, or if you are pregnant or breastfeeding. Domperidone can raise prolactin and may cause breast tenderness or discharge
• Do not stop a long course of the PPI abruptly, and tell your doctor about difficulty swallowing, vomiting blood, black stools or unintended weight loss

Storage

• Store in a dry place at a temperature not exceeding 30°C. Protect from light, as printed on the carton
• Capsule should be swallowed whole; do not open or crush
• Keep out of reach of children

Disclaimer

Schedule H prescription drug – to be sold by retail on the prescription of a Registered Medical Practitioner only. Domperidone-containing medicines should be used at the lowest effective dose for the shortest possible time, and are not suitable for everyone. This information is for general awareness and is not a substitute for professional medical advice, diagnosis or treatment.