Iscept Forte 5mg/850mg Tablet is an oral anti-diabetic combination medicine used to manage blood sugar levels in adults with Type 2 diabetes mellitus. It combines Glibenclamide, a sulfonylurea that stimulates the pancreas to release more insulin, with Metformin, a biguanide that reduces glucose production in the liver and improves the body’s sensitivity to insulin. Together, these two mechanisms work to lower blood glucose more effectively than either medicine alone, helping patients whose sugar levels are not adequately controlled on a single anti-diabetic agent or on diet and exercise alone.
Glibenclamide works by acting on the beta cells of the pancreas, encouraging them to secrete additional insulin in response to meals. Metformin complements this by decreasing the amount of glucose released by the liver and by helping muscle and fat cells use the available insulin more efficiently. This dual-action approach is why fixed-dose combinations like Iscept Forte are commonly prescribed once diet, exercise, and single-drug therapy are no longer sufficient to keep blood sugar within target range.
Iscept Forte should be taken exactly as advised by a physician, usually with meals to reduce the chance of stomach upset and to minimise the risk of low blood sugar (hypoglycemia). Regular monitoring of blood glucose and periodic kidney and liver function checks are recommended while on this medicine. Patients should maintain consistent meal timing, avoid skipping meals, and limit alcohol intake, since alcohol can increase the risk of hypoglycemia and lactic acidosis. This medicine works best when combined with a balanced, sugar-controlled diet and regular physical activity.
Key composition:
- Glibenclamide 5mg
- Metformin Hydrochloride 850mg
Common points to keep in mind:
- Take with food to reduce gastrointestinal discomfort and hypoglycemia risk
- Do not skip or delay meals after taking this medicine
- Inform your doctor about kidney, liver, or heart conditions before starting
- Avoid alcohol consumption during treatment
- Keep a fast-acting sugar source handy in case of low blood sugar symptoms
- Store in a cool, dry place away from direct sunlight, out of reach of children
Iscept Forte is manufactured under the supervision of Eris Lifesciences Limited / Pure and Cure Healthcare Pvt Ltd and marketed by Strides Shasun Ltd. It should only be used under medical supervision, and any change in dose must be made by a qualified healthcare provider based on periodic blood sugar review.















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