Grandem 1 mg Tablet

Grandem 1 mg Tablet – Granisetron 1 mg by Aristo

Grandem 1 mg Tablet from Aristo Pharmaceuticals contains Granisetron 1 mg, a selective 5-HT3 receptor antagonist. Chemotherapy and radiotherapy damage cells in the gut lining, which release large amounts of serotonin; that serotonin triggers the vomiting reflex through 5-HT3 receptors. Granisetron blocks those receptors, so the signal never reaches the vomiting centre. It is one of the most effective options for the severe nausea of cancer treatment, and is also used after surgery. Strip of 10 tablets. Prescription medicine.

Key Features

• Granisetron 1 mg – selective 5-HT3 receptor antagonist
• Highly effective against chemotherapy-induced nausea and vomiting
• Also used for radiotherapy and post-operative nausea
• May be taken with or without food
• Strip of 10 tablets from Aristo Pharmaceuticals Pvt Ltd.

Composition

• Granisetron – 1 mg per tablet

Refer to the pack label and package insert for the complete list of excipients.

Uses & Benefits

• Prevention and treatment of chemotherapy-induced nausea and vomiting
• Controls nausea and vomiting caused by radiotherapy
• Prevention and treatment of post-operative nausea and vomiting
• Helps patients keep down food and fluids during cancer treatment
• Reduces the dehydration and weight loss that severe vomiting causes
• Makes it easier to complete a planned course of treatment

Directions for Use

• Take exactly as prescribed by your doctor
• Swallow the tablet whole with water; do not chew, crush or break it
• May be taken with or without food
• For chemotherapy, take the dose about an hour before treatment starts – prevention works far better than trying to stop vomiting once it has begun
• Continue for the full course your doctor sets, even on days you feel well

Precautions

• Constipation is the commonest side effect – 5-HT3 blockers slow the bowel. Keep fluids up and tell your doctor if it becomes troublesome
• Other effects include headache, diarrhoea, weakness, fever and abdominal pain
• Tell your doctor about heart rhythm problems or if you take other medicines that prolong the QT interval – this class can affect heart rhythm
• Use with caution in severe kidney disease
• Safety in pregnancy and breastfeeding is not established – discuss with your doctor
• Ask your doctor about alcohol; seek urgent care for chest pain, fainting or an irregular heartbeat

Storage

• Store below 30°C in a dry place
• Keep tablets in the original blister, protected from light and moisture
• Keep out of reach of children

Disclaimer

Prescription medicine – not to be sold by retail without the prescription of a Registered Medical Practitioner. This information is for general awareness only and is not a substitute for professional medical advice, diagnosis or treatment. Anti-emetic therapy during cancer treatment must be planned by your treating oncologist.