Duotrol Tablet

Duotrol Tablet

Duotrol Tablet is USV Private Limited’s glibenclamide and metformin combination, with Glibenclamide 5 mg and Metformin Hydrochloride 500 mg in each uncoated tablet. USV has a long track record in Indian diabetes care, and Duotrol is positioned as an economical dual-therapy option for adults with type 2 diabetes whose sugar levels are not controlled by lifestyle measures and a single medicine. The sulfonylurea component increases insulin output from the pancreas while metformin lowers hepatic glucose production and improves peripheral insulin sensitivity. Each strip holds 10 tablets.

Key Features

• Contains Glibenclamide 5 mg and Metformin Hydrochloride 500 mg
• Economical dual-therapy option for adults with type 2 diabetes
• One tablet in place of two separate anti-diabetic medicines
• From USV Private Limited, a long-established Indian diabetes-care company
• Strip of 10 uncoated tablets, with 30 and 50 tablet packs for repeat courses

Composition

• Glibenclamide – 5 mg
• Metformin Hydrochloride – 500 mg

Uses & Benefits

• Management of type 2 diabetes mellitus in adults when diet and exercise alone are not enough
• Combines two complementary actions in one tablet, reducing the number of pills taken each day
• Glibenclamide stimulates the pancreas to release more insulin, lowering blood glucose after meals
• Metformin lowers glucose production by the liver and improves the body’s response to insulin
• Helps bring fasting and post-meal sugar readings closer to the target range set by your doctor
• Better long-term glycaemic control supports protection of the eyes, kidneys, nerves and heart

Directions for Use

• Take exactly as prescribed, generally one tablet with or right after a meal
• Swallow whole with water – do not crush, split or chew
• Do not skip meals after taking a dose, as this raises the risk of low blood sugar
• If you miss a dose, take it when you remember unless the next is due – never double up
• Continue routine glucose monitoring and doctor follow-ups

Precautions

• Prescription-only medicine – take it strictly as directed and never adjust the dose on your own
• Can cause hypoglycaemia (low blood sugar); carry glucose or sugar and learn the warning signs such as sweating, shakiness, hunger and confusion
• Nausea, a metallic taste, loose stools, bloating and reduced appetite are the most common effects and usually settle with time
• Not suitable in significant kidney or liver impairment, severe infection, dehydration or diabetic ketoacidosis because of the risk of lactic acidosis
• Tell your doctor before any surgery or contrast X-ray scan, and avoid alcohol, which increases both hypoglycaemia and lactic acidosis risk
• Avoid in pregnancy and breastfeeding unless your doctor advises otherwise; keep the strip out of reach of children

Storage

• Store below 30°C in a cool, dry place
• Keep the tablets in the original strip, protected from light and moisture
• Do not use after the printed expiry date and keep away from children

Disclaimer

This information is for general awareness only and is not a substitute for medical advice. Glibenclamide with metformin is a prescription medicine; please use it only under the supervision of a qualified doctor and continue your prescribed blood-sugar monitoring.