Cernos Depot 1000mg Injection

Cernos Depot Injection

Cernos Depot from Sun Pharma is a long-acting testosterone injection used in testosterone replacement therapy for men with medically confirmed hypogonadism. Each 4 ml ampoule holds 1000 mg of testosterone undecanoate suspended in an oily vehicle. The long undecanoate ester is what makes it a depot: the oil forms a reservoir in the muscle and releases testosterone slowly, so one injection lasts around 10 to 14 weeks instead of the two to three weeks typical of shorter esters. It is given by a healthcare professional after a formal diagnosis, and requires ongoing blood monitoring.

Key Features

• Testosterone Undecanoate 1000 mg per 4 ml single-use ampoule.
• Depot action – one injection typically covers 10 to 14 weeks.
• Far fewer injections than shorter-acting testosterone esters.
• Produces steadier testosterone levels with less peak-and-trough swing.
• Point-cut ampoule; marketed by Sun Pharma Laboratories.

Composition / Key Ingredients

Each ml contains:

• Testosterone Undecanoate – 250 mg (equivalent to Testosterone 157.9 mg)
• Excipients – q.s. in an oily vehicle

Each 4 ml ampoule therefore delivers 1000 mg of testosterone undecanoate. Please refer to the pack label for the complete list of ingredients.

Uses & Benefits

• Testosterone replacement in primary and secondary hypogonadism in men.
• Helps restore energy, mood and normal libido where these are driven by low testosterone.
• Supports maintenance of muscle mass and bone mineral density.
• Supports normal red blood cell production.
• Long dosing interval suits men who cannot manage frequent injections.
• Steadier levels than short-ester testosterone, with fewer symptom swings.

Directions for Use

• To be administered by a healthcare professional only – the pack states dosage is as directed by the endocrinologist.
• Given as a very slow, deep intramuscular injection into the gluteal muscle. Not for intravenous use.
• A common schedule is a second dose 6 weeks after the first, then every 10 to 14 weeks.
• Inspect the solution first – do not use if it contains visible particles.
• Single use only. Use immediately after opening and discard any unused solution.

Precautions

• Schedule H prescription drug. The label states: “Not to be sold by retail without the prescription of an Endocrinologist.”
• Contraindicated in known or suspected cancer of the prostate or male breast. Prostate assessment and PSA are required before starting.
• Risk of pulmonary oil microembolism (POME) and anaphylaxis. You should be observed for a period after the injection; report coughing, chest tightness, dizziness or breathlessness immediately.
• Regular monitoring of testosterone, haematocrit, PSA and liver function is required throughout treatment.
• Tell your doctor about heart, liver or kidney disease, high blood pressure, sleep apnoea, epilepsy or migraine.
• Not for use by women, and not for boys before puberty. Testosterone can harm an unborn baby.

Storage

• Store at room temperature, protected from light.
• Do not freeze or refrigerate.
• Keep out of the reach of children.

Frequently Asked Questions

How often do I need this injection?
Usually the second dose is given about 6 weeks after the first to build levels up, then roughly every 10 to 14 weeks. Your endocrinologist sets the exact interval from your blood results – it is not the same for everyone.

Can I inject it myself at home?
No. This is a 4 ml oily injection that must be given slowly and deep into the gluteal muscle by a trained professional. Injecting it incorrectly, or accidentally into a blood vessel, is what causes the POME reaction described above.

How soon will I notice a difference?
Libido and mood often respond within the first few weeks. Changes in muscle mass, body composition and bone density build up over several months of consistent treatment.

What is POME and how likely is it?
Pulmonary oil microembolism happens when a little of the oily solution reaches the bloodstream and travels to the lungs. It is uncommon, and usually brief, but it is the reason you are asked to wait and be observed after the injection rather than leave straight away.

Do I really need regular blood tests?
Yes. Testosterone therapy can raise your haematocrit (thickening the blood) and affects PSA. These are checked before you start and at intervals afterwards, and the dose or schedule is adjusted based on them.

Can I use it to build muscle at the gym?
No. Cernos Depot is a prescription treatment for diagnosed testosterone deficiency, not a performance or bodybuilding product. Taking testosterone without a deficiency suppresses your own production, can reduce fertility, and carries cardiovascular and liver risks.

Disclaimer: Cernos Depot Injection is a Schedule H prescription medicine, dispensed against a valid prescription and administered under medical supervision. This information is for education only and is not a substitute for professional medical advice, diagnosis or treatment.