Barinat 4 mg Tablet

Barinat 4 mg Tablet – Baricitinib 4 mg by Natco

Barinat 4 mg Tablet from Natco Pharma contains Baricitinib 4 mg, a targeted synthetic disease-modifying drug of the JAK inhibitor class. Rheumatoid arthritis is driven by cytokines that dock on immune cells and instruct them to attack the joint lining; that instruction is carried inward by Janus kinase enzymes. Baricitinib blocks JAK1 and JAK2, cutting the message off before it reaches the nucleus, so the joint inflammation is suppressed at its source rather than merely masked. Specialists also prescribe it for severe alopecia areata, where the same pathway drives the immune attack on hair follicles. Pack of 14 tablets. Specialist prescription medicine.

Key Features

• Baricitinib 4 mg – film-coated tablet
• JAK1 and JAK2 inhibitor – targeted synthetic DMARD
• Suppresses joint inflammation at the signalling level
• Also used by specialists for severe alopecia areata
• Pack of 14 tablets from Natco Pharma Ltd.

Composition

• Baricitinib – 4 mg per film-coated tablet

Composition as printed on the pack. Refer to the package insert for the complete list of excipients.

Uses & Benefits

• Reduces joint pain, swelling and morning stiffness in rheumatoid arthritis
• Slows the joint damage that untreated inflammatory arthritis causes
• An oral option for patients who have not responded to methotrexate or to injectable biologics
• Taken once daily as a tablet – no injections or infusions
• Also prescribed by specialists for severe alopecia areata and severe atopic dermatitis
• Works within weeks rather than months for many patients

Directions for Use

• Take exactly as prescribed by your specialist – the dose is set for you and is often reduced in kidney impairment
• Swallow the tablet whole with water; do not chew, crush or break it
• May be taken with or without food, at the same time each day
• Do not stop or restart on your own – stopping suddenly can let the disease flare
• Keep every blood-test appointment your doctor books; this medicine is monitored, not simply dispensed

Precautions

• Baricitinib suppresses the immune system. Serious infections – including tuberculosis, shingles and hepatitis B reactivation – can occur. Your doctor will screen you for TB and hepatitis before you start
• Tell your doctor immediately about fever, cough, weight loss, night sweats or a painful blistering rash, and stop the tablet until you are assessed
• Regular blood tests are required – blood counts, liver enzymes and cholesterol are all monitored during treatment
• There is a raised risk of blood clots in the legs and lungs. Report leg swelling or pain, breathlessness or chest pain urgently
• JAK inhibitors carry warnings about major cardiac events and certain cancers, particularly in older smokers – your doctor weighs this before prescribing
• Not for use in pregnancy; effective contraception is needed during treatment and for a week after. Avoid breastfeeding
• Do not take live vaccines while on treatment. Tell your doctor about kidney or liver disease and every other medicine you take

Storage

• Store below 30°C, protected from moisture and direct light
• Keep the tablets in their original container
• Keep out of reach of children

Disclaimer

Prescription medicine – to be sold by retail on the prescription of a specialist only. This information is for general awareness and is not a substitute for professional medical advice, diagnosis or treatment. Baricitinib requires screening before treatment and regular blood-test monitoring during it.