Abec-L Tablet

Abec-L Tablet – Abacavir 600 mg + Lamivudine 300 mg by Emcure

Abec-L Tablet from Emcure Pharmaceuticals Ltd. is a fixed-dose combination of Abacavir 600 mg and Lamivudine 300 mg (Abacavir & Lamivudine Tablets IP). Both are nucleoside reverse transcriptase inhibitors (NRTIs): they block the enzyme HIV uses to copy itself, so the amount of virus in the blood falls, and CD4 cell counts recover. Combining both actives in one once-daily film-coated tablet makes long-term antiretroviral therapy simpler to follow. Supplied as a bottle of 30 tablets. Schedule H prescription drug.

Key Features

• Two NRTIs in one once-daily tablet – simpler ART regimen
• Abacavir 600 mg + Lamivudine 300 mg, Indian Pharmacopoeia grade
• Film-coated tablet; may be taken with or without food
• Manufactured by Emcure Pharmaceuticals Ltd., India

Composition

• Abacavir (as Abacavir Sulphate IP) – 600 mg
• Lamivudine IP – 300 mg

Uses & Benefits

• Treatment of HIV-1 infection as part of combination antiretroviral therapy
• Prevents HIV from multiplying, lowering viral load in the blood
• Raises CD4 white blood cell counts to strengthen immune defence
• Once-daily dosing supports better long-term adherence
• Helps reduce the risk of HIV-related opportunistic infections
• Two medicines in one tablet means fewer pills each day

Directions for Use

• Take exactly as prescribed by your doctor – usually one tablet once daily
• Swallow the tablet whole with water; do not chew, crush or break it
• Take at the same time each day, with or without food
• Do not stop or change the dose on your own, even if you feel well
• If you miss a dose, take it as soon as you remember unless the next dose is near – never double up

Precautions

• HLA-B*5701 screening before starting abacavir is recommended by treatment guidelines
• Common side effects include hypersensitivity, headache, insomnia, rash, nausea, vomiting and decreased appetite
• Use with caution in liver or kidney disease; dose adjustment may be needed
• Avoid alcohol; not recommended in pregnancy and may be unsafe while breastfeeding – consult your doctor
• May cause dizziness – avoid driving until you know how it affects you

Storage

• Store below 30°C, protected from moisture and direct light
• Keep the bottle tightly closed; do not remove the desiccant
• Keep out of reach of children

Disclaimer

Schedule H prescription drug – not to be sold by retail without the prescription of a Registered Medical Practitioner. This information is for general awareness only and is not a substitute for professional medical advice, diagnosis or treatment. Antiretroviral therapy must be started, changed and monitored only by a qualified HIV specialist.