Renvorab-20 Tablet

Renvorab-20 Tablet – Rabeprazole Gastro-Resistant Tablets IP 20 mg by Leeford

Renvorab-20 from Leeford Healthcare is Rabeprazole Gastro-Resistant Tablets IP 20 mg. Rabeprazole is the newest of the widely used proton pump inhibitors and it has one clear technical advantage over the rest. Every drug in this class is a “prodrug” that has to be chemically converted before it can block an acid pump, and how fast that conversion happens depends on how acidic the surroundings are. Omeprazole and its relatives need a strongly acidic environment; rabeprazole converts across a much wider pH range and does it faster, so it begins working sooner and produces useful acid suppression from the first dose rather than after several days. It is also the least dependent on the CYP2C19 liver enzyme, so it varies less between patients and interacts with fewer other medicines. Manufactured by Windlas Biotech, Dehradun. Swallow whole with water. Strip of 15 tablets.

Key Features

• Rabeprazole Sodium IP 20 mg, gastro-resistant (enteric-coated) tablets
• The fastest-acting PPI – activates over a wider pH range than the others
• The least CYP2C19-dependent of the class, so fewer interactions
• Colours: Ferric Oxide Yellow USP-NF and Titanium Dioxide IP
• Strip of 15 tablets. Marketed by Leeford Healthcare Ltd., made by Windlas Biotech

Composition

• Rabeprazole Sodium IP – 20 mg
• Excipients q.s. Colours: Ferric Oxide Yellow USP-NF & Titanium Dioxide IP. As printed on the carton

Uses & Benefits

• Treats GERD, heartburn, acid regurgitation and reflux oesophagitis
• Heals gastric and duodenal ulcers and helps prevent recurrence
• Used with antibiotics to eradicate H. pylori
• Used in Zollinger-Ellison syndrome and other acid hypersecretory states
• Protects the stomach lining in long-term NSAID users, as prescribed
• Once-daily dosing before breakfast for most people

Directions for Use

• Swallow the tablet whole with water. Do not crush or chew it – the gastro-resistant coating is what protects the drug from stomach acid
• Take it 30 to 60 minutes before a meal, usually before breakfast, or exactly as your doctor directs
• Take it at the same time each day and complete the full course even if symptoms settle early
• If you miss a dose, take it when you remember unless the next is nearly due. Never take two together
• Avoid or limit alcohol, smoking and trigger foods during treatment

Precautions

• Take it 30 to 60 minutes before food. A proton pump inhibitor can only disable acid pumps that are already switched on, and eating is what switches them on
• Long-term use is not harmless – low magnesium, low vitamin B12, reduced calcium absorption, higher fracture risk and gut infections are all associated with prolonged acid suppression. Use the lowest dose for the shortest time that controls symptoms
• Do not stop a long course abruptly; acid can rebound above where it started and the symptoms can be mistaken for relapse
• Tell your doctor about difficulty swallowing, vomiting blood, black stools or unintended weight loss – acid suppression can mask a serious problem
• Tell your doctor about liver disease, low magnesium, and every other medicine you take – including methotrexate, digoxin, antifungals, HIV medicines and warfarin
• Headache, diarrhoea, nausea, wind and stomach pain can occur and are usually mild

Storage

• Store protected from light and moisture at a temperature not exceeding 30°C, as printed on the carton
• Tablet should be swallowed whole with water; do not crush or chew
• Keep all medicines out of reach of children

Disclaimer

Schedule H prescription drug – to be sold by retail on the prescription of a Registered Medical Practitioner only. Acid-suppressing medicines are meant for a defined course, not indefinite self-treatment. This information is for general awareness and is not a substitute for professional medical advice, diagnosis or treatment.