Trantas-MF Tablet

Trantas-MF Tablet – Tranexamic Acid 500 mg + Mefenamic Acid 250 mg by Intas

Trantas-MF from Intas Pharmaceuticals is a film-coated tablet of Tranexamic Acid IP 500 mg and Mefenamic Acid IP 250 mg, prescribed for heavy and painful menstrual periods. Mefenamic acid is worth a note of its own: among the NSAIDs it is a fenamate, and fenamates do something the others do not – besides inhibiting the cyclo-oxygenase enzymes that make prostaglandins, they also block the prostaglandin receptors directly. That dual action is the reason mefenamic acid has held its place in period pain for decades despite newer, cheaper alternatives. Paired with tranexamic acid, which prevents clots in the endometrium from dissolving too early, this tablet addresses flow and pain by unrelated routes, so neither has to be pushed to a high dose. Non-hormonal, and taken only on the days it is needed. Pack of 1 x 10 tablets.

Key Features

• Tranexamic Acid IP 500 mg + Mefenamic Acid IP 250 mg, film-coated
• Covers both heavy flow and period pain in a single tablet
• Mefenamic acid blocks prostaglandin synthesis and prostaglandin receptors
• Non-hormonal – nothing to take between periods
• Pack of 1 x 10 tablets, marketed by Intas Pharmaceuticals Ltd.

Composition

• Tranexamic Acid IP – 500 mg
• Mefenamic Acid IP – 250 mg
• Colours: Yellow Oxide of Iron & Titanium Dioxide IP. Excipients q.s. As printed on the pack

Uses & Benefits

• Controls heavy menstrual bleeding and the accompanying cramping pain
• Two unrelated mechanisms, so neither drug has to be pushed to a high dose
• Mefenamic acid is a fenamate – it blocks prostaglandin receptors as well as their synthesis
• Non-hormonal, with no effect on the cycle, ovulation or fertility
• Taken only on the days of heavy, painful flow
• Replaces taking a painkiller and an antifibrinolytic separately

Directions for Use

• Swallow the tablet whole with water
• Take it with or straight after food – the NSAID component irritates an empty stomach
• Dosage as directed by the physician
• Do not add other NSAIDs on top of it
• Stop at the end of the prescribed course

Precautions

• This contains an NSAID. Avoid it with a stomach ulcer, previous gastrointestinal bleeding, severe kidney or liver disease, uncontrolled heart failure, or aspirin/NSAID-sensitive asthma
• Tell your doctor about any previous blood clot, stroke or heart attack before taking tranexamic acid
• Do not combine with combined hormonal contraceptives without specialist advice
• Interacts with blood thinners, lithium, methotrexate, diuretics and blood pressure medicines – give your doctor the full list
• Seek help urgently for black stools, vomiting blood, severe abdominal pain, rash, facial swelling, breathlessness, calf pain or visual change
• Persistent heavy bleeding needs investigation for a cause, not just symptom control

Storage

• Store in a cool, dry and dark place. Protect from light, as printed on the pack
• Keep the tablets in the blister until use
• Keep the medicines out of reach of children

Disclaimer

Schedule H prescription drug – to be sold by retail on the prescription of a Registered Medical Practitioner only. This information is for general awareness and is not a substitute for professional medical advice, diagnosis or treatment. Heavy or abnormal bleeding always needs a cause to be found; do not treat it with an antifibrinolytic on your own.