Eptus 25 mg Tablet

Eptus 25 mg Tablet – Eplerenone 25 mg by Glenmark

Eptus 25 from Glenmark Pharmaceuticals contains Eplerenone IP 25 mg in a film-coated tablet. Eplerenone is a selective aldosterone antagonist, prescribed mainly to protect the heart after a heart attack and in chronic heart failure. Aldosterone is a hormone that tells the kidney to hold on to salt and water, and in a failing heart the body produces far too much of it – raising blood pressure, loading the heart with fluid, and over time driving the scarring that stiffens heart muscle. Eplerenone blocks the receptor that hormone acts on. Its selectivity is the point of difference from spironolactone, the older drug in this class: spironolactone also blocks androgen and progesterone receptors, which is why it commonly causes breast tenderness and enlargement in men. Eplerenone largely avoids that. Strip of 15 tablets. Prescription medicine.

Key Features

• Eplerenone IP 25 mg film-coated tablet
• Selective aldosterone antagonist – blocks the salt-retaining hormone at its receptor
• Avoids the breast enlargement that limits spironolactone in men
• Used after heart attack, in chronic heart failure and in resistant high blood pressure
• Strip of 15 tablets from Glenmark Pharmaceuticals Ltd.

Composition

• Eplerenone IP – 25 mg per film-coated tablet
• Colours – Ferric Oxide Yellow USP-NF, Ferric Oxide Red USP-NF and Titanium Dioxide IP

Uses & Benefits

• Improves survival when started after a heart attack with reduced heart function
• Reduces hospital admissions and symptoms in chronic heart failure
• Lowers blood pressure that has not responded to other medicines
• Reduces the fluid retention that causes breathlessness and swollen ankles
• Slows the fibrosis that stiffens heart muscle over time
• Free of the breast enlargement and tenderness associated with spironolactone

Directions for Use

• Take exactly as prescribed, usually once daily at the same time
• Swallow the tablet whole with water; may be taken with or without food
• Keep every blood test appointment. Potassium and kidney function are checked before starting, within the first week, and regularly after – this is not optional with this medicine
• Do not take potassium supplements or potassium-based salt substitutes unless your doctor specifically tells you to
• Do not stop or change the dose on your own, even if you feel well

Precautions

• Raised blood potassium is the main risk, and it can be dangerous. Report muscle weakness, tingling, an irregular or slow heartbeat, or unusual tiredness without delay
• Avoid potassium supplements, salt substitutes containing potassium, and potassium-sparing diuretics such as spironolactone or amiloride
• Tell your doctor about kidney disease – eplerenone is not used when kidney function is significantly reduced
• Do not take with ketoconazole, itraconazole, clarithromycin, ritonavir or nelfinavir – they block its breakdown and push potassium dangerously high
• Tell your doctor about type 2 diabetes with kidney involvement, liver disease, or if you take ACE inhibitors, ARBs, NSAIDs or lithium
• Dizziness, tiredness and diarrhoea can occur. Discuss pregnancy and breastfeeding with your doctor before use

Storage

• Store protected from moisture, at a temperature not exceeding 30°C, as printed on the pack
• Keep tablets in the original blister until use
• Keep out of reach of children

Disclaimer

Prescription medicine – to be sold by retail on the prescription of a Registered Medical Practitioner only. This information is for general awareness and is not a substitute for professional medical advice, diagnosis or treatment. Eplerenone requires regular blood monitoring; never take it without medical supervision.