NovoMix 30 Penfill 100 IU/ml

NovoMix 30 Penfill 100 IU/ml

NovoMix 30 Penfill is a premixed biphasic insulin aspart suspension from Novo Nordisk, supplied as a 3 ml cartridge containing 100 units per ml. Each cartridge combines two forms of the same modern analogue insulin: 30% fast-acting soluble insulin aspart to cover the rise in blood glucose that follows a meal, and 70% protamine-crystallised insulin aspart that is released slowly to provide steady background cover between meals. This single-cartridge combination lets adults and children with type 1 or type 2 diabetes mellitus manage both mealtime and basal insulin needs with fewer daily injections. The Penfill cartridge is designed for use with Novo Nordisk reusable insulin delivery devices such as NovoPen, together with NovoFine needles.

Key Features

• Premixed 30/70 biphasic insulin aspart – mealtime and background cover in one cartridge.
• Rapid onset from the soluble aspart fraction, so it can be taken immediately before a meal.
• 3 ml Penfill cartridge delivering 100 units per ml (300 units per cartridge).
• Compatible with NovoPen reusable devices and NovoFine needles for accurate dose dialling.
• Manufactured by Novo Nordisk, a global leader in insulin therapy.

Composition

• Each ml contains Insulin Aspart (r-DNA origin) I.P. 100 U (3.5 mg)
• 30% as soluble insulin aspart, 70% as insulin aspart protamine crystals
• Phenol 1.5 mg and Metacresol 1.72 mg as preservatives
• Excipients q.s.

Uses

• Control of blood glucose in type 1 diabetes mellitus.
• Control of blood glucose in type 2 diabetes mellitus when oral medicines alone are not sufficient.
• Twice-daily regimens where both mealtime and basal insulin cover are required.

How to Use

• Use only as directed by your doctor. Dose is individual and is set by your treating physician.
• Roll and tip the cartridge gently until the suspension looks uniformly white and cloudy before every injection. Never inject it if it stays clumped or clear.
• Load the cartridge into a compatible Novo Nordisk pen and attach a fresh NovoFine needle for each dose.
• Inject subcutaneously into the abdomen, thigh, upper arm or buttock, rotating the site each time to avoid lipodystrophy.
• Give the dose immediately before a meal, and eat within a few minutes of injecting.
• A Penfill cartridge is for one person only – never share cartridges, pens or needles.

Precautions

• Schedule H drug. To be sold by retail on the prescription of a Registered Medical Practitioner only. It is dangerous to take this preparation except under medical supervision.
• Carry a fast-acting source of sugar at all times; skipped meals, extra exercise or alcohol can trigger hypoglycaemia.
• Tell your doctor about kidney or liver disease, thyroid problems, or any change in your diet or activity, as your dose may need adjusting.
• Do not switch insulin brand, type or strength without medical advice.
• Monitor blood glucose regularly, particularly when starting or changing the dose.
• Take care while driving or operating machinery if your glucose control is unstable.

Side Effects

• Hypoglycaemia (low blood sugar) – the most common effect
• Injection site reactions such as redness, swelling or itching
• Lipodystrophy (thickening or pitting of skin) if sites are not rotated
• Weight gain
• Rash, itching or allergic reactions

Storage

• Store unused cartridges between 2°C and 8°C in a refrigerator. Do not freeze, and protect from light.
• A cartridge in use may be kept at room temperature below 30°C for up to 4 weeks.
• Keep out of the reach and sight of children. Destroy the Penfill after use.

Legal Disclaimer: NovoMix 30 Penfill is a prescription-only medicine. This information is for educational purposes and does not replace the advice of a qualified doctor or pharmacist. Always follow the dose and regimen prescribed for you, and consult your physician before making any change to your insulin therapy.