Bioglandin Injection
Bioglandin Injection contains Alprostadil (500 mcg), a synthetic version of the naturally occurring Prostaglandin E1 (PGE1). This medication is a powerful vasodilator that acts by relaxing smooth muscle tissues and widening blood vessels. It serves two primary clinical purposes: in adult men, it is used as a second-line treatment for erectile dysfunction (ED), especially when oral medications are ineffective or unsuitable. In neonates (newborns), it is a life-saving intervention used to temporarily maintain the patency of the ductus arteriosus in infants born with congenital heart defects. Keeping this vital blood vessel open, it ensures adequate oxygenation and blood circulation until surgical correction can be performed.
Key Features
- Directly relaxes vascular smooth muscles to significantly increase blood flow to targeted areas.
- Critical for “ductal-dependent” heart conditions, maintaining a bridge to life-saving surgery for newborns.
- Effective for treating erectile dysfunction by increasing intracavernosal blood pressure and flow.
- When used for ED, effects are typically observed within 5 to 20 minutes of administration.
- Often used by specialists during diagnostic tests to evaluate the vascular health of the penis.
Key Ingredients
- Alprostadil (500 mcg): The active prostaglandin E1 analogue responsible for muscle relaxation and vessel widening.
- Ethanol/Saline Vehicle: Provides a sterile medium for the active drug (specific formulation varies by brand/intended route).
Precautions
- Professional Administration: This is a high-alert medication that must be administered by a healthcare professional, especially when used for cardiac conditions in infants.
- Priapism Risk: When used for ED, seek immediate medical attention for any erection lasting longer than 4 hours, as this can cause permanent damage.
- Neonatal Monitoring: Infants must be closely monitored for apnea (interrupted breathing), which occurs in approximately 10–12% of treated neonates.
- Cardiovascular Effects: May cause a sudden drop in blood pressure (hypotension), dizziness, or flushing.
- Contraindications: Do not use if you have conditions predisposing you to priapism (e.g., sickle cell anemia, multiple myeloma) or if you have a penile implant.
How to Use
- For Neonates: Administered as a continuous intravenous (IV) infusion in a neonatal intensive care unit (NICU) by specialized staff.
- For Erectile Dysfunction: Injected directly into the side of the penis (intracavernosal) using a very fine needle, as directed by a urologist.
- Dosage: The exact dose is highly individualized based on the patient’s weight (for infants) or response (for adults).
- Storage: Most formulations require refrigeration (2°C to 8°C). Do not freeze. Check specific label instructions for “cold chain” requirements.
- Single Use: Vials are generally for single use only; any unused portion should be discarded immediately to maintain sterility.
Legal Disclaimer: The product is guaranteed to be 100% genuine. Product images are for illustrative purposes only. Packaging/labels may vary due to manufacturer updates. This is a potent prescription-only injectable; it should only be used under the direct supervision of a qualified medical specialist.
