Ramiven 150 mg Tablet contains Abemaciclib 150 mg, a targeted prescription anticancer medicine used to treat selected types of hormone receptor-positive (HR-positive), HER2-negative breast cancer. It may be prescribed for eligible adults with high-risk early breast cancer or advanced or metastatic breast cancer. Abemaciclib belongs to a class of medicines called cyclin-dependent kinase 4 and 6 inhibitors, commonly known as CDK4/6 inhibitors. It works by blocking the CDK4 and CDK6 proteins that help cancer cells grow and divide, thereby slowing or stopping their progression. Ramiven 150 mg Tablet may be prescribed with endocrine therapy such as tamoxifen, an aromatase inhibitor, or fulvestrant. The treatment combination, dosage, and duration depend on the cancer stage, previous treatments, treatment response, and the oncologist’s recommendations.

Key Features

• Contains Abemaciclib 150 mg: A selective CDK4 and CDK6 inhibitor.
• Targeted Anticancer Treatment: Helps block proteins involved in cancer-cell growth and division.
• Used for Selected Breast Cancers: Prescribed for eligible HR-positive and HER2-negative breast cancer.
• May Be Combined with Endocrine Therapy: Used with hormonal treatment according to the prescribed treatment plan.
• Oral Tablet: Taken by mouth under strict oncologist supervision.

Active Ingredient

• Abemaciclib 150 mg: A targeted kinase inhibitor that blocks CDK4 and CDK6 proteins involved in cancer cell division.

Uses

• HR-positive, HER2-negative, node-positive early breast cancer with a high risk of recurrence.
• HR-positive, HER2-negative advanced or metastatic breast cancer as part of endocrine-based treatment.
• Advanced or metastatic breast cancer that has progressed following previous endocrine therapy.
• Selected advanced breast cancer cases following previous endocrine therapy and chemotherapy.

How to Use

• Take Ramiven 150 mg Tablet exactly as prescribed by your oncologist.
• Swallow the tablet whole with water.
• Do not crush, chew, split, or dissolve the tablet.
• Do not take tablets that are cracked, broken, or damaged.
• The tablet may be taken with or without food.
• Take each dose at approximately the same time every day.
• If you miss a dose or vomit after taking it, take the next dose at the scheduled time. Do not take an additional dose.
• Do not change the dose or stop treatment without consulting your oncologist.

Precautions

• Use only under the supervision of an oncologist experienced in anticancer treatment.
• Regular blood tests are required to monitor blood-cell counts, liver function, and treatment response.
• Inform your doctor if you have liver disease, kidney problems, lung disease, an active infection, or a history of blood clots.
• Inform your healthcare provider about all prescription medicines, non-prescription medicines, vitamins, supplements, and herbal products you use.
• Avoid grapefruit and grapefruit-containing products because they may affect the amount of abemaciclib in the blood.
• Effective contraception should be used during treatment and for the period recommended by the oncologist after the final dose.
• Breastfeeding is not recommended during treatment and for the advised period after stopping the medicine.

Warning

• Severe Diarrhoea: Abemaciclib may cause serious diarrhoea, dehydration, or infection. Contact your healthcare provider at the first sign of loose stools.
• Low Blood Cell Counts: Treatment may cause neutropenia, anaemia, leukopenia, or reduced platelet counts.
• Liver Problems: Abemaciclib may increase liver enzymes and cause liver injury.
• Lung Problems: Interstitial lung disease or pneumonitis, including severe cases, may occur.
• Blood Clots: Treatment may increase the risk of deep-vein thrombosis or pulmonary embolism.
• Seek immediate medical attention for fever, breathing difficulty, persistent cough, chest pain, unusual bleeding, severe weakness, or swelling and pain in an arm or leg.
• This medicine can harm an unborn baby and should not be used during pregnancy unless specifically directed by an oncology specialist.

Common Side

• Diarrhoea.
• Nausea or vomiting.
• Fatigue and weakness.
• Reduced appetite.
• Abdominal discomfort.
• Headache.
• Hair thinning or hair loss.
• Low white blood cell, red blood cell, or platelet counts.
• Increased risk of infections.

Storage

• Store below 30°C or according to the instructions printed on the original packaging.
• Protect the tablets from moisture, excessive heat, and direct sunlight.
• Keep the tablets in their original blister packaging until use.
• Do not use tablets that are cracked, broken, or damaged.
• Keep out of reach of children and pets.

Legal Disclaimer: Ramiven 150 mg Tablet is a prescription anticancer medicine intended for use only under the supervision of a qualified oncologist. It may cause serious adverse effects and requires regular medical and laboratory monitoring. This information is provided for educational purposes only and should not replace professional medical advice, diagnosis, treatment, or the instructions provided with the medicine.

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