Ramiven 200 mg Tablet contains Abemaciclib 200 mg, a targeted anticancer medicine used for selected types of hormone receptor-positive (HR-positive), HER2-negative breast cancer. This strength may be prescribed as monotherapy for eligible adults with advanced or metastatic breast cancer following previous treatments. Abemaciclib belongs to a class of medicines called cyclin-dependent kinase 4 and 6 inhibitors, commonly known as CDK4/6 inhibitors. It works by blocking CDK4 and CDK6 proteins involved in cancer-cell growth and division, helping slow or stop the progression of cancer cells. Ramiven 200 mg Tablet must be taken only under the supervision of a qualified oncologist. The dosage, treatment schedule, duration, and any dose reduction depend on the patient’s condition, previous treatments, treatment response, and tolerability.

Key Features

• Contains Abemaciclib 200 mg: A selective CDK4 and CDK6 inhibitor.
• Targeted Anticancer Treatment: Blocks proteins involved in cancer cell division.
• Used for Selected Breast Cancers: Prescribed for eligible HR-positive, HER2-negative breast cancer.
• Oral Treatment: Supplied as a tablet for oral administration.
• Requires Regular Monitoring: Blood counts, liver function, and treatment response must be monitored.

Active Ingredient

• Abemaciclib 200 mg: A targeted kinase inhibitor that blocks CDK4 and CDK6 proteins involved in the growth and multiplication of cancer cells.

Uses

• Selected HR-positive, HER2-negative advanced breast cancer.
• Selected HR-positive, HER2-negative metastatic breast cancer.
• Monotherapy following disease progression after endocrine therapy and previous chemotherapy in appropriate patients.
• Other treatment regimens are only used when specifically prescribed by an oncologist.

How to Use

• Take Ramiven 200 mg Tablet exactly as prescribed by your oncologist.
• Swallow the tablet whole with water.
• Do not crush, chew, split, or dissolve the tablet.
• Do not take tablets that are cracked, broken, or otherwise damaged.
• The tablet may be taken with or without food.
• Take each dose at approximately the same time every day.
• If you miss a dose or vomit after taking it, take the next dose at its scheduled time.
• Do not take an additional or double dose to replace a missed dose.
• Do not change the dose or stop treatment without consulting your oncologist.

Precautions

• Use only under the supervision of an oncologist experienced in anticancer treatment.
• Regular complete blood counts and liver-function tests may be required during treatment.
• Inform your doctor if you have liver disease, kidney problems, lung disease, an active infection, or a history of blood clots.
• Inform your healthcare provider about all prescription medicines, non-prescription medicines, vitamins, supplements, and herbal products you use.
• Avoid grapefruit and grapefruit-containing products during treatment.
• Effective contraception should be used during treatment and for the period recommended by the oncologist after the final dose.
• Breastfeeding is not recommended during treatment and for the advised period after the last dose.

Warning

• Severe Diarrhoea: Abemaciclib may cause serious diarrhoea, dehydration, or infection. Contact your healthcare provider when loose stools first occur.
• Low Blood Cell Counts: Treatment may cause neutropenia, anaemia, leukopenia, or reduced platelet counts.
• Liver Problems: Abemaciclib may increase liver enzymes and cause liver injury.
• Lung Problems: Interstitial lung disease or pneumonitis, including serious cases, may occur.
• Blood Clots: Treatment may increase the risk of deep-vein thrombosis or pulmonary embolism.
• Seek immediate medical attention for fever, breathing difficulty, persistent cough, chest pain, severe weakness, unusual bleeding, or swelling and pain in an arm or leg.
• This medicine may harm an unborn baby and should not be used during pregnancy unless specifically directed by an oncology specialist.

Common Side Effects

• Diarrhoea.
• Nausea or vomiting.
• Fatigue and weakness.
• Abdominal discomfort.
• Reduced appetite.
• Headache.
• Hair thinning or hair loss.
• Low white blood cell, red blood cell, or platelet counts.
• Increased susceptibility to infections.

Storage

• Store at room temperature between 20°C and 25°C, or according to the instructions printed on the original packaging.
• Protect the tablets from moisture, excessive heat, and direct sunlight.
• Keep the tablets in their original packaging until use.
• Do not use tablets that are cracked, broken, or damaged.
• Keep out of reach of children and pets.

Legal Disclaimer: Ramiven 200 mg Tablet is a prescription anticancer medicine intended for use only under the supervision of a qualified oncologist. It may cause serious adverse effects and requires regular medical and laboratory monitoring. This information is provided for educational purposes only and should not replace professional medical advice, diagnosis, treatment, or the instructions supplied with the medicine.

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